Wednesday, December 31, 2025

Axsome - Priority Review for Alzheimer's Disease Agitation

We first wrote about the prospect of the company addressing this unmet need here Agitation in Alzheimer's Disease - An Unmet NeedThe therapy, if approved could allow easier caregiver services, that keep patients in their home setting, avoiding institutional care. The company completed all phases of clinical trials, and filed a new drug application recently (NDA) for AXS-05 for the indication of Alzheimer's Disease Agitation. Axsome was notified by the FDA that the application has been accepted with priority review and a decision date (PDUFA) of April 30th, 2026. This is great news as it could be the only non-antipsychotic drug to be approved for this indication.  Receiving priority review, which includes a shortened time frame for review, increases the chances of approval significantly. The stocks reaction as anticipated, is very positive chart below. 

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