Tuesday, June 4, 2024

AXS-14 for Fibromyalgia

Axsome's vast pipeline includes AXS-14, (esreboxetine) a novel treatment for fibromyalgia. AXS-14 brings a new mechanism of action, a highly selective and potent norepinephrine reuptake inhibitor which was successful in phase 2 and 3 clinical trials. There are currently three FDA approved drugs to treat fibromyalgia. 

  • Lyrica (2007
  • Cymbalta (2008)
  • Savella (2009)
Axsome currently has AXS-14 patent pending, Google Patent. If approved, the patent would expect to extend out to around 2042. Another smaller company Tonix is expected to apply for FDA approval for their fibromyalgia drug, TNX-102 SL, in the second half of 2024. Below is a chart of Axsome which has trended around the $75.00 level most of 2024. Thank you for reading.

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